NMPARegulatory IntelligenceRegulation
China GMP (2010 Revision)

Good Manufacturing Practice for Drugs (China)

China's GMP for drugs (2010 Revision), administered by the NMPA under the Drug Administration Law. Structured similarly to EU GMP with a main text and appendices (e.g. sterile products), it raised Chinese GMP substantially toward international norms.

LAST REVISED
March 2011
PRODUCT AREAS
SterileSolid DoseBiotechApi
SCOPE & APPLICABILITY

Drug manufacturers supplying the Chinese market. Appendices cover sterile drugs, APIs, biological products, and traditional Chinese medicine.

KEY REQUIREMENTS
  • 01Operate a compliant pharmaceutical quality system
  • 02Apply the relevant product appendix (e.g. sterile)
  • 03Maintain validation and data integrity
IMPLEMENTATION TIPS
Engage in-country regulatory expertise for NMPA inspection and dossier-language requirements
REVISION NOTES

The 2010 Revision (effective 2011) substantially upgraded China GMP; the 2019 Drug Administration Law introduced the MAH system.

China GMP (2010 Revision): frequently asked questions

Quick answers to common questions about China GMP (2010 Revision).

What is China GMP (2010 Revision)?

China GMP (2010 Revision) — Good Manufacturing Practice for Drugs (China) — is a regulation issued by the National Medical Products Administration (China). China's GMP for drugs (2010 Revision), administered by the NMPA under the Drug Administration Law. Structured similarly to EU GMP with a main text and appendices (e.g. sterile products), it raised Chinese GMP substantially toward international norms.

Who does China GMP (2010 Revision) apply to?

Drug manufacturers supplying the Chinese market. Appendices cover sterile drugs, APIs, biological products, and traditional Chinese medicine.

What are the key requirements of China GMP (2010 Revision)?

NMPA China GMP (2010 Revision) requires, among other things: Operate a compliant pharmaceutical quality system; Apply the relevant product appendix (e.g. sterile); Maintain validation and data integrity.

When was China GMP (2010 Revision) last updated?

The current version of China GMP (2010 Revision) dates from March 2011. The 2010 Revision (effective 2011) substantially upgraded China GMP; the 2019 Drug Administration Law introduced the MAH system.

RELATED STANDARDS
RELATED FDA RECALLS
where Documentation & Change Control control fails
See all Documentation & Change Control recalls →

Live openFDA recalls SPEQ maps to this standard’s topics — a SPEQ interpretation, not an FDA classification.

THIS STANDARD IN PRACTICE

Recall domain is a SPEQ mapping of this standard’s topics, not an FDA classification.

Weekly Briefing

Track the standards that move

When China GMP (2010 Revision) — or any GxP requirement — is revised, recalled against, or clarified by new guidance, the Weekly GxP Briefing surfaces it. Free, one email a week.

Read a past issue →