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MHRA (UK) · DRUG SAFETY UPDATE30 April 2026

Nasal decongestant sprays and drops containing xylometazoline hydrochloride / oxymetazoline hydrochloride: increased risk of rebound congestion, rhinitis medicamentosa, and tachyphylaxis with overuse

Alert type
Drug Safety Update
Alert date
30 April 2026
Regulator
MHRA (United Kingdom)
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Alert details are published by the UK MHRA on GOV.UK; SPEQ surfaces them for reference and is not affiliated with or endorsed by the MHRA. The authoritative notice is on gov.uk.