Food & Dietary Supplements

Human food and dietary supplements — preventive controls, HACCP, allergen and pathogen control, and supply-chain safety.

What this page does not claim

SPEQ decodes published standards and does not determine which apply to your product. An industry’s counts measure SPEQ’s coverage, not the size of its rulebook.

WHAT THIS INDUSTRY COVERS

Food & Dietary Supplements covers human food and the supplements regulated alongside it — manufacturing, processing, packing, and holding under preventive-controls and HACCP frameworks. Quality here is food safety: keeping pathogens, allergens, and physical and chemical hazards out of the food supply, and proving the controls that do it.

REGULATORY LANDSCAPE

Anchored by FDA’s FSMA rules (21 CFR 117 preventive controls, 111 for supplements, plus FSVP and food-defense), the Codex Alimentarius (HACCP; CXC 1-1969), and ISO 22000 for food-safety management. Retailer-driven GFSI schemes add a strong private-standard layer on top of the regulatory baseline.

WHY THIS PRODUCT IS HARD TO CONTROL

Volume and time. Food is produced at a scale and consumed on a timescale where testing your way to safety is arithmetically impossible — a pathogen distributed through one lot in a few units will not be found by any sampling plan a plant can afford, and the product is often eaten before a result would return. So the control model inverts: identify the hazards, establish the points where they can actually be controlled, monitor those continuously, and treat the record of control as the evidence. HACCP is not a quality system borrowed from pharma; it is the answer to a problem pharma does not have at this scale.

WHAT QUALITY MEANS HERE

01

Hazard analysis & preventive controls

A food-safety plan built on hazard analysis with risk-based preventive controls, monitoring, corrective action, and verification (FSMA 21 CFR 117).

02

HACCP & sanitation

Critical control points, sanitation, and environmental monitoring for pathogens — the operational core of food safety (Codex, ISO 22000).

03

Allergen & label control

Allergen management and accurate labelling — undeclared allergens are the single largest driver of food recalls.

04

Supply-chain & food defense

Foreign-supplier verification (FSVP) and food-defense planning against intentional adulteration across an increasingly global supply chain.

16
Standards decoded
4
GxP disciplines
219
FDA recalls · 12 mo →

FDA groups food, dietary-supplement, cosmetic & animal-food recalls in one bucket — this count spans that bucket.

STANDARDS SPEQ DECODES · 16

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21 CFR Part 117FDAHIGH INSPECTION RISK
Current Good Manufacturing Practice, Hazard Analysis, and Risk-Based Preventive Controls for Human Food
21 CFR Part 111FDAHIGH INSPECTION RISK
Current Good Manufacturing Practice for Dietary Supplements
Codex CXC 1-1969Codex
General Principles of Food Hygiene
ISO 22000:2018ISO
Food safety management systems — Requirements for any organization in the food chain
21 CFR Part 1, Subpart LFDA
Foreign Supplier Verification Programs (FSVP)
21 CFR Part 121FDA
Mitigation Strategies to Protect Food Against Intentional Adulteration
21 CFR Part 507FDA
Current Good Manufacturing Practice and Preventive Controls for Food for Animals
ISO/IEC 17025:2017ISO
General requirements for the competence of testing and calibration laboratories
ILAC MRAILAC
ILAC Mutual Recognition Arrangement
Reg. (EC) 852/2004EC
Regulation on the Hygiene of Foodstuffs
21 CFR Part 123FDA
Fish and Fishery Products (Seafood HACCP)
21 CFR Part 112FDA
Standards for the Growing, Harvesting, Packing, and Holding of Produce for Human Consumption
21 CFR Part 106FDAHIGH INSPECTION RISK
Infant Formula Requirements: Current Good Manufacturing Practice, Quality Control Procedures, and Quality Factors
USP <2750>USP
Manufacturing Practices for Dietary Supplements
21 CFR Part 558FDA
New Animal Drugs for Use in Animal Feeds
ISO 19011:2018ISO
Guidelines for Auditing Management Systems

WHERE QUALITY FAILS

  • Undeclared allergens from labelling or changeover errors
  • Pathogen contamination (Listeria, Salmonella, E. coli) from sanitation gaps
  • Foreign material in product
  • Unverified foreign suppliers entering the supply chain

KEY REGULATORY BODIES

Derived from the 16 standards SPEQ decodes for this industry.

Food & Dietary Supplements: frequently asked questions

Quick answers to common questions about GxP in Food & Dietary Supplements.

What regulations govern food manufacturing?

In the US, FDA’s FSMA rules — 21 CFR 117 (preventive controls), 111 (dietary supplements), plus foreign-supplier verification and food-defense requirements. Internationally, the Codex Alimentarius HACCP standard (CXC 1-1969) and ISO 22000, with retailer-driven GFSI schemes adding a private-standard layer.

What is the difference between HACCP and preventive controls?

HACCP centres on critical control points for identified hazards (Codex, ISO 22000). FSMA’s preventive controls (21 CFR 117) build on hazard analysis but require risk-based preventive controls, monitoring, corrective action, and verification that reach beyond classic CCPs.

What causes the most food recalls?

Undeclared allergens — from labelling or changeover errors — are the single largest driver of food recalls, followed by pathogen contamination such as Listeria, Salmonella, and E. coli from sanitation gaps.