PLANREFERENCE OUTLINE

Laboratory Proficiency Testing Programme

Programme using external comparison to find bias internal quality control cannot see, because a laboratory consistently wrong is consistently wrong against its own controls. Enrolment mapped from the live test menu, samples handled exactly as routine work, a results register, unacceptable results investigated to a cause with the already-reported results reviewed, and consistent bias inside the acceptable range treated as a trend rather than a pass. Maps to ISO 15189:2022 and 42 CFR Part 493.

What a template is not

A template is a document baseline to adapt inside your own quality system. SPEQ does not approve, validate, or take responsibility for what you issue from it, and using one is not evidence of compliance.

CHECKING ACCESS

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REGULATIONS MAPPED
ISO 15189:202242 CFR Part 493
DOCUMENT TYPE
Plan
LAST UPDATED
August 2026
PURPOSE

Internal quality control detects drift against your own values. It cannot detect bias, because a laboratory that is consistently wrong is consistently wrong against its own controls too. Interlaboratory comparison is the only routine mechanism measuring a laboratory against the outside world, and its most useful output is the consistent bias inside the acceptable range that never fails a round.

What's Inside

Enrolment mapped from the live test menu, with a documented alternative where no scheme exists
Handling rules requiring proficiency samples be processed exactly as routine work, by routine staff
A results register carrying the deviation and z-score, not only the acceptable or unacceptable verdict
Investigation of unacceptable results to a cause, including review of results already reported out
Trend analysis kept separate from the pass or fail outcome, so consistent bias becomes visible
Outcomes fed into management review and into the individual competence records they bear on
Programme review when the test menu, method or instrument changes, so enrolment stays matched

How to Use It

1Map enrolment from the live test menu and re-map whenever it changes; gaps otherwise surface at assessment rather than at your own review.
2Handle proficiency samples exactly as routine work — special handling measures the best case and, under the US regime, referral is prohibited.
3Record the deviation and z-score for every round, because a pass recorded without its numbers cannot be trended afterwards.
4When a result is unacceptable, review the patient or study results already reported alongside it before closing the investigation.
5Treat consistent bias inside the acceptable range as a trend to act on; it never fails a round, which is exactly why it is missed.
6Feed outcomes into management review and competence records, so a repeated finding reaches the people who can resource a fix.
DOCUMENT CONTENTS

The full section structure of this template — every section and sub-section, so you can use it as a baseline for your own site document.

Document Control
Document InformationApproval SignaturesRevision HistoryDistribution List
1Why This Exists
2Enrolment Mapped From the Test Menu
3Handling — Exactly as Routine Samples
4Results Register
5Investigation of Unacceptable Results
6Trend, Not Only Pass
7Feeding Review and Competence
REGULATORY CONTEXT

ISO 15189:2022 requires participation in interlaboratory comparison, evaluation of the results obtained, and action where performance is unsatisfactory; 42 CFR Part 493 sets the US proficiency testing enrolment, handling and performance requirements, including the referral prohibitions. Neither decides which schemes you enrol in, what you do where no scheme exists, or what counts as an actionable trend inside the acceptable range. Those determinations are the laboratory’s. The programme structure is SPEQ practitioner synthesis.

MAPPED STANDARDS
ISO 15189:202242 CFR Part 493
Browse the standards catalog →