ECRegulatory IntelligenceRegulation
Regulation (EU) 2019/6

Veterinary Medicinal Products

The EU regulation governing the authorisation, manufacture, import, distribution, and pharmacovigilance of veterinary medicinal products. Applying since January 2022, it replaced Directive 2001/82/EC, expanded scope (including euthanasia substances), and substantially strengthened provisions to combat antimicrobial resistance.

LAST REVISED
January 2022
PRODUCT AREAS
Veterinary
SCOPE & APPLICABILITY

Veterinary medicinal products across the EU market — from manufacturing authorisation and GMP through distribution and safety surveillance.

KEY REQUIREMENTS
  • 01Hold appropriate manufacturing/import authorisation and comply with veterinary GMP
  • 02Operate a pharmacovigilance system for veterinary medicines
  • 03Apply antimicrobial-resistance controls and use restrictions
  • 04Meet EU product-database and traceability obligations
IMPLEMENTATION TIPS
Prioritise the antimicrobial-resistance provisions — they are the regulation’s signature change
Stand up veterinary pharmacovigilance distinct from your human-medicine GVP where both apply
Confirm database/traceability submissions; they are a new compliance surface
REVISION NOTES

Adopted December 2018 and applicable since 28 January 2022, replacing Directive 2001/82/EC with expanded scope and stronger antimicrobial-resistance measures.

Regulation (EU) 2019/6: frequently asked questions

Quick answers to common questions about Regulation (EU) 2019/6.

What is Regulation (EU) 2019/6?

Regulation (EU) 2019/6 — Veterinary Medicinal Products — is a regulation issued by the European Commission — EudraLex (European Union). The EU regulation governing the authorisation, manufacture, import, distribution, and pharmacovigilance of veterinary medicinal products. Applying since January 2022, it replaced Directive 2001/82/EC, expanded scope (including euthanasia substances), and substantially strengthened provisions to combat antimicrobial resistance.

Who does Regulation (EU) 2019/6 apply to?

Veterinary medicinal products across the EU market — from manufacturing authorisation and GMP through distribution and safety surveillance.

What are the key requirements of Regulation (EU) 2019/6?

EC Regulation (EU) 2019/6 requires, among other things: Hold appropriate manufacturing/import authorisation and comply with veterinary GMP; Operate a pharmacovigilance system for veterinary medicines; Apply antimicrobial-resistance controls and use restrictions; Meet EU product-database and traceability obligations.

When was Regulation (EU) 2019/6 last updated?

The current version of Regulation (EU) 2019/6 dates from January 2022. Adopted December 2018 and applicable since 28 January 2022, replacing Directive 2001/82/EC with expanded scope and stronger antimicrobial-resistance measures.

RELATED STANDARDS
RELATED FDA RECALLS
where Documentation & Change Control control fails
See all Documentation & Change Control recalls →

Live openFDA recalls SPEQ maps to this standard’s topics — a SPEQ interpretation, not an FDA classification.

THIS STANDARD IN PRACTICE

Recall domain is a SPEQ mapping of this standard’s topics, not an FDA classification.

Weekly Briefing

Track the standards that move

When Regulation (EU) 2019/6 — or any GxP requirement — is revised, recalled against, or clarified by new guidance, the Weekly GxP Briefing surfaces it. Free, one email a week.

Read a past issue →