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FEDERAL REGISTER · NOTICEAugust 28, 2026NOTICE — NO LEGAL EFFECTOPEN FOR COMMENT

Compounding Animal Drugs From Bulk Drug Substances: Compounding Under CGMP in Federally-Registered Facilities; Draft Guidance for Industry; Availability; Agency Information Collection Activities; Proposed Collection; Comment Request

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Document type
Notice
Agency
Health and Human Services Department
Published
August 28, 2026
Comments close
November 27, 2026
Document number
2026-17580
ABSTRACT

The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a draft guidance for industry (GFI) #256B entitled "Compounding Animal Drugs from Bulk Drug Substances: Compounding under CGMP in Federally-Registered Facilities." This draft guidance, when finalized, will describe FDA's current thinking regarding the circumstances under which we generally do not intend to take action against the compounding of animal drug products from bulk drug substances (BDS) when done in accordance with Current Good Manufacturing Practice (CGMP) at drug production facilities that are registered with FDA.

Abstract as published in the Federal Register.

The comment window is still open until November 27, 2026. The comment window is open. Check the document itself for what comments are being solicited on and what weight they carry. Submit comments through the Federal Register document below.

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