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FEDERAL REGISTER · NOTICEAugust 14, 2026NOTICE — NO LEGAL EFFECTOPEN FOR COMMENT

Container Closure Systems for Human Drugs and Biological Products; Draft Guidance for Industry; Availability

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Document type
Notice
Agency
Health and Human Services Department
Published
August 14, 2026
Comments close
October 13, 2026
Document number
2026-16638
ABSTRACT

The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a draft guidance for industry entitled "Container Closure Systems for Human Drugs and Biological Products." This document provides guiding principles for evaluating the quality of container closure systems (CCSs) used to package drugs and biological products, for human use. This includes CCSs that are also device constituent parts of combination products and CCSs used to package the drug or biological product constituent parts of combination products.

Abstract as published in the Federal Register.

The comment window is still open until October 13, 2026. The comment window is open. Check the document itself for what comments are being solicited on and what weight they carry. Submit comments through the Federal Register document below.

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