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FEDERAL REGISTER · PROPOSED RULEAugust 11, 2026PROPOSED — NOT IN FORCEOPEN FOR COMMENT

Substances Generally Recognized as Safe

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Document details are published in the U.S. Federal Register; SPEQ surfaces them for reference and is not affiliated with or endorsed by the FDA or the Office of the Federal Register. The authoritative text is on federalregister.gov.

STATUSPROPOSED — NOT IN FORCE
PROPOSED EFFECTIVE—
COMMENTS CLOSEDec 9, 2026 · in 42 days
APPLIES TO · SPEQ TAGFoodVeterinary
Document type
Proposed Rule
Agency
Health and Human Services Department
Published
August 11, 2026
Comments close
December 9, 2026
Document number
2026-16296
CFR references
21 CFR 170, 21 CFR 570
Docket
FDA-2025-N-3262
RIN
0910-AJ02
ABSTRACT

The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).

Abstract as published in the Federal Register.

The comment window is still open until December 9, 2026. This is a proposal, and the comment window is the point at which the text is still negotiable — industry input here shapes what the final rule says. Submit comments through the Federal Register document below.

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The complete document — every provision, the docket, and the comment instructions — is published in the Federal Register. SPEQ surfaces and indexes it for reference; the authoritative text lives on federalregister.gov.

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