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FEDERAL REGISTER · PROPOSED RULEAugust 11, 2026PROPOSED — NOT IN FORCEOPEN FOR COMMENT

Substances Generally Recognized as Safe

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Document details are published in the U.S. Federal Register; SPEQ surfaces them for reference and is not affiliated with or endorsed by the FDA or the Office of the Federal Register. The authoritative text is on federalregister.gov.

Document type
Proposed Rule
Agency
Health and Human Services Department
Published
August 11, 2026
Comments close
December 9, 2026
Document number
2026-16296
ABSTRACT

The Food and Drug Administration (FDA or we) is proposing to require the submission of generally recognized as safe (GRAS) notices for the use of a human or animal food substance purported to be GRAS under the conditions of its intended use under the Federal Food, Drug, and Cosmetic Act (FD&C Act).

Abstract as published in the Federal Register.

The comment window is still open until December 9, 2026. This is a proposal, and the comment window is the point at which the text is still negotiable — industry input here shapes what the final rule says. Submit comments through the Federal Register document below.

READ THE FULL DOCUMENT

The complete document — every provision, the docket, and the comment instructions — is published in the Federal Register. SPEQ surfaces and indexes it for reference; the authoritative text lives on federalregister.gov.

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