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FEDERAL REGISTER · PROPOSED RULEMarch 18, 2026PROPOSED — NOT IN FORCE

Medical Devices; Radiology Devices; Classification of Blood Irradiators

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Document details are published in the U.S. Federal Register; SPEQ surfaces them for reference and is not affiliated with or endorsed by the FDA or the Office of the Federal Register. The authoritative text is on federalregister.gov.

Document type
Proposed Rule
Agency
Health and Human Services Department
Published
March 18, 2026
Comments close
May 18, 2026
Document number
2026-05320
ABSTRACT

The Food and Drug Administration (FDA) is proposing to classify blood irradiator devices (product code MOT), unclassified preamendments devices, as follows: blood irradiator devices intended to prevent transfusion-associated graft-versus-host disease into class II (special controls) with premarket notification and blood irradiator devices intended to prevent metastasis into class III (premarket approval) to provide a reasonable assurance of safety and effectiveness of these devices. Elsewhere in this issue of the Federal Register, FDA is issuing a proposed order proposing to require the filing of a premarket approval application for blood irradiator devices intended to prevent metastasis.

Abstract as published in the Federal Register.

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