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FEDERAL REGISTER · NOTICEFebruary 6, 2026NOTICE — NO LEGAL EFFECT

E22 General Considerations for Patient Preference Studies; International Council for Harmonisation; Draft Guidance for Industry; Availability

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Document type
Notice
Agency
Health and Human Services Department
Published
February 6, 2026
Comments close
April 7, 2026
Document number
2026-02324
ABSTRACT

The Food and Drug Administration (FDA, Agency, or we) is announcing the availability of a draft guidance for industry entitled "E22 General Considerations for Patient Preference Studies." The draft guidance was prepared under the auspices of the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). When finalized, this guidance will provide general principles for the use, design, conduct, analysis, and submission of patient preference studies (PPS) aimed at informing drug development, regulatory submission and evaluation, drug approvals, and maintenance of such approvals.

Abstract as published in the Federal Register.

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