A drug shortage is a quality failure with a body count.
Live FDA drug shortage data (openFDA), grouped by status, availability, and therapeutic area. The FDA’s own root-cause analysis puts manufacturing and quality problems at the centre of the shortage crisis — which is why SPEQ treats the shortage list as a quality-system signal, not just a supply-chain one.
By initial FDA posting date. openFDA lists active shortages, so older cohorts thin as entries resolve.
The FDA’s 2019 report Drug Shortages: Root Causes and Potential Solutions found the dominant drivers are not scarcity of raw materials but a lack of incentives to produce, and manufacturing/quality problems that force production to stop. Mature quality systems — the difference a QMM assessment measures — are what keep a line running.
| Drug | Company | Therapeutic area | Availability | Status | Posted |
|---|---|---|---|---|---|
| Dexmedetomidine Hydrochloride InjectionInjection | Azurity Pharmaceuticals, Inc | Anesthesia | Available | Current | 2020-04-10 |
| Carboplatin InjectionInjection | Teyro Labs | Oncology | Unavailable | Current | 2023-04-28 |
| Quinapril/Hydrochlorothiazide TabletTablet | Chartwell Molecular Holdings LLC | Cardiovascular | Available | Current | 2023-01-19 |
| Clonazepam TabletTablet | Teva Pharmaceuticals USA, Inc. | Neurology | Limited | Current | 2023-03-10 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Lannett Company, Inc. | Psychiatry | Available | Current | 2023-09-20 |
| Quinapril Hydrochloride TabletTablet | Chartwell Molecular Holdings LLC | Cardiovascular | Available | Current | 2023-01-19 |
| Methylphenidate Hydrochloride Tablet, Extended ReleaseTablet | Vertical Pharmaceuticals, LLC | Psychiatry | Available | Current | 2023-07-26 |
| Methylphenidate Hydrochloride Tablet, Extended ReleaseTablet | Vertical Pharmaceuticals, LLC | Psychiatry | Available | Current | 2023-07-26 |
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Oryza Pharmaceuticals Inc. | Psychiatry | Unavailable | Current | 2022-10-12 |
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Teva Pharmaceuticals USA, Inc. | Psychiatry | Available | Current | 2022-10-12 |
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Teva Pharmaceuticals USA, Inc. | Psychiatry | Available | Current | 2022-10-12 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Lannett Company, Inc. | Psychiatry | Available | Current | 2023-07-14 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Elite Laboratories, Inc. | Psychiatry | Limited | Current | 2023-07-14 |
| Quinapril Hydrochloride TabletTablet | Chartwell Molecular Holdings LLC | Cardiovascular | Available | Current | 2023-01-19 |
| Clonazepam TabletTablet | Cheplapharm Arzneimittel GmbH | Neurology | Available | Current | 2023-03-10 |
| Carboplatin InjectionInjection | Teva Pharmaceuticals USA, Inc. | Oncology | Limited | Current | 2023-04-28 |
| Atropine Sulfate InjectionInjection | Medefil, Inc. | Anesthesia | Available | Current | 2012-01-01 |
| Hydroxocobalamin InjectionInjection | BTG International Inc. | Other | Available | Current | 2024-11-04 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Elite Laboratories, Inc. | Psychiatry | Limited | Current | 2023-07-14 |
| Peginterferon alfa-2a InjectionInjection | pharmaand GmbH (pharma&) | Antiviral | Available | Current | 2025-01-24 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Lannett Company, Inc. | Psychiatry | Available | Current | 2023-07-14 |
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Teva Pharmaceuticals USA, Inc. | Psychiatry | Available | Current | 2022-10-12 |
| Isocarboxazid TabletTablet | Lifsa Drugs LLC | Psychiatry | Unavailable | Current | 2026-04-16 |
| Furosemide Oral SolutionOral Solution | Hikma Pharmaceuticals USA, Inc. | Cardiovascular | Limited | Current | 2026-03-31 |
| Lorazepam InjectionInjection | Hikma Pharmaceuticals USA, Inc. | Neurology | Unavailable | Current | 2018-09-05 |
Data: U.S. FDA openFDA drug/shortages API, which lists activeshortages (Current or To Be Discontinued) — it carries no per-record cause field, so SPEQ makes no root-cause claim on individual drugs; the quality framing above is cited FDA context. openFDA publishes shortage data for drugs only; SPEQ’s cross-industry coverage lives in the recall Explorer(drug, device & food).