[ FDA DRUG SHORTAGES TRACKER ]

A drug shortage is a quality failure with a body count.

Live FDA drug shortage data (openFDA), grouped by status, availability, and therapeutic area. The FDA’s own root-cause analysis puts manufacturing and quality problems at the centre of the shortage crisis — which is why SPEQ treats the shortage list as a quality-system signal, not just a supply-chain one.

1,000
Active shortages tracked
844
Current
155
To be discontinued
214
Flagged unavailable
21% flagged unavailable · latest update 2026-07-27 · source: openFDA drug/shortages
NEW SHORTAGES POSTED · MONTHLY

By initial FDA posting date. openFDA lists active shortages, so older cohorts thin as entries resolve.

ACTIVE SHORTAGES BY THERAPEUTIC CATEGORY · TOP 10
WHY THIS SITS UNDER QUALITY, NOT LOGISTICS

The FDA’s 2019 report Drug Shortages: Root Causes and Potential Solutions found the dominant drivers are not scarcity of raw materials but a lack of incentives to produce, and manufacturing/quality problems that force production to stop. Mature quality systems — the difference a QMM assessment measures — are what keep a line running.

The economics of quality →FDA QMM framework →
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1,166 matching shortages
DrugCompanyTherapeutic areaAvailabilityStatusPosted
Fluticasone Propionate and Salmeterol Xinafoate Aerosol, MeteredGlaxoSmithKlinePulmonary/Allergy—To Be Discontinued2026-07-27
Fluticasone Propionate and Salmeterol Xinafoate Aerosol, MeteredGlaxoSmithKlinePulmonary/Allergy—To Be Discontinued2026-07-27
Fluticasone Propionate and Salmeterol Xinafoate Aerosol, MeteredGlaxoSmithKlinePulmonary/Allergy—To Be Discontinued2026-07-27
Lopinavir and Ritonavir Oral SolutionOral SolutionAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Lopinavir and Ritonavir TabletTabletAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Lopinavir and Ritonavir TabletTabletAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Ritonavir TabletTabletAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Ritonavir Oral PowderOral PowderAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Lopinavir and Ritonavir TabletTabletAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTabletGranules Pharmaceuticals Inc.PsychiatryUnavailableCurrent2022-10-12
Lopinavir and Ritonavir TabletTabletAbbVie Inc.Antiviral—To Be Discontinued2026-07-24
Lidocaine Hydrochloride InjectionInjectionHospira, Inc., a Pfizer CompanyAnesthesiaAvailableCurrent2012-02-22
Bendamustine Hydrochloride Injection, SolutionInjectionCephalon, LLC (a wholly owned subsidiary of Teva Pharmaceutical Industries, Ltd.)Oncology—To Be Discontinued2026-07-23
Sterile Water InjectionInjectionHospira, Inc., a Pfizer CompanyOtherLimitedCurrent2021-12-03
Lisdexamfetamine Dimesylate CapsuleCapsuleSun Pharmaceutical Industries, Inc.PsychiatryLimitedCurrent2023-07-14
Bupivacaine Hydrochloride InjectionInjectionHospira, Inc., a Pfizer CompanyAnesthesiaAvailableCurrent2018-02-20
Dextrose Monohydrate 50% InjectionInjectionHospira, Inc., a Pfizer CompanyEndocrinology/MetabolismUnavailableCurrent2022-01-13
Lidocaine Hydrochloride InjectionInjectionHospira, Inc., a Pfizer CompanyAnesthesiaAvailableCurrent2012-02-22
Midazolam Hydrochloride InjectionInjectionHospira, Inc., a Pfizer CompanyAnesthesiaAvailableCurrent2020-04-02
Lisdexamfetamine Dimesylate CapsuleCapsuleSun Pharmaceutical Industries, Inc.PsychiatryLimitedCurrent2023-07-14
Morphine Sulfate SuppositorySuppositoryPadagis US LLCAnalgesia/Addiction—To Be Discontinued2026-07-23
Lidocaine Hydrochloride InjectionInjectionHospira, Inc., a Pfizer CompanyAnesthesiaAvailableCurrent2012-02-22
Belladonna and Opium SuppositorySuppositoryPadagis US LLCAnalgesia/Addiction—To Be Discontinued2026-07-23
Technetium TC-99M Pyrophosphate Kit InjectionInjectionSun Pharmaceutical Industries, Inc.Medical ImagingUnavailableCurrent2023-12-27
Lisdexamfetamine Dimesylate Tablet, ChewableTablet, ChewableSun Pharmaceutical Industries, Inc.PsychiatryAvailableCurrent2023-07-14
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Data: U.S. FDA openFDA drug/shortages API, which lists activeshortages (Current or To Be Discontinued) — it carries no per-record cause field, so SPEQ makes no root-cause claim on individual drugs; the quality framing above is cited FDA context. openFDA publishes shortage data for drugs only; SPEQ’s cross-industry coverage lives in the recall Explorer(drug, device & food).