A drug shortage is a quality failure with a body count.
Live FDA drug shortage data (openFDA), grouped by status, availability, and therapeutic area. The FDA’s own root-cause analysis puts manufacturing and quality problems at the centre of the shortage crisis — which is why SPEQ treats the shortage list as a quality-system signal, not just a supply-chain one.
By initial FDA posting date. openFDA lists active shortages, so older cohorts thin as entries resolve.
The FDA’s 2019 report Drug Shortages: Root Causes and Potential Solutions found the dominant drivers are not scarcity of raw materials but a lack of incentives to produce, and manufacturing/quality problems that force production to stop. Mature quality systems — the difference a QMM assessment measures — are what keep a line running.
| Drug | Company | Therapeutic area | Availability | Status | Posted |
|---|---|---|---|---|---|
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Epic Pharma, LLC | Psychiatry | Limited | Current | 2022-10-12 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
| Rifampin CapsuleCapsule | Epic Pharma, LLC | Anti-Infective | Available | Current | 2021-12-22 |
| Rifampin CapsuleCapsule | Epic Pharma, LLC | Anti-Infective | Available | Current | 2021-12-22 |
| Dextrose Monohydrate 50% InjectionInjection | Amphastar Pharmaceuticals, Inc. | Endocrinology/Metabolism | Available | Current | 2022-01-13 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
| Rifampin CapsuleCapsule | Epic Pharma, LLC | Anti-Infective | Unavailable | Current | 2021-12-22 |
| Echothiophate Iodide Ophthalmic SolutionOphthalmic Solution | Fera Pharmaceuticals | Ophthalmology | Available | Current | 2019-09-24 |
| Lidocaine Hydrochloride InjectionInjection | Amphastar Pharmaceuticals, Inc. | Anesthesia | Limited | Current | 2012-02-22 |
| Desmopressin Acetate SpraySpray | Apotex Corp. | Hematology | Limited | Current | 2021-03-12 |
| Morphine Sulfate InjectionInjection | Amphastar Pharmaceuticals, Inc. | Analgesia/Addiction | Available | Current | 2018-12-06 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
| Midazolam Hydrochloride InjectionInjection | Avet Pharmaceuticals, Inc. | Anesthesia | Unavailable | Current | 2020-04-02 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
| Furosemide InjectionInjection | Avet Pharmaceuticals, Inc. | Cardiovascular | Available | Current | 2020-04-07 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Apotex Corp. | Psychiatry | Unavailable | Current | 2023-11-01 |
| Furosemide InjectionInjection | Avet Pharmaceuticals, Inc. | Cardiovascular | Limited | Current | 2020-04-07 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Apotex Corp. | Psychiatry | Available | Current | 2023-11-01 |
| Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate TabletTablet | Alvogen | Psychiatry | Available | Current | 2022-10-12 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Apotex Corp. | Psychiatry | Available | Current | 2023-11-01 |
| Rifampin CapsuleCapsule | Epic Pharma, LLC | Anti-Infective | Unavailable | Current | 2021-12-22 |
| Lorazepam InjectionInjection | Amphastar Pharmaceuticals, Inc. | Neurology | Available | Current | 2018-05-03 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Apotex Corp. | Psychiatry | Available | Current | 2023-11-01 |
| Lisdexamfetamine Dimesylate CapsuleCapsule | Alvogen | Psychiatry | Available | Current | 2023-07-14 |
Data: U.S. FDA openFDA drug/shortages API, which lists activeshortages (Current or To Be Discontinued) — it carries no per-record cause field, so SPEQ makes no root-cause claim on individual drugs; the quality framing above is cited FDA context. openFDA publishes shortage data for drugs only; SPEQ’s cross-industry coverage lives in the recall Explorer(drug, device & food).