· ECOSYSTEM · RING 4

Responsible Person (RP) & Qualified Person (QP) Services

External assurance & governance — Professional & assurance

The contract professionals who hold two named legal roles in the EU/UK system: the Qualified Person (QP) who certifies each batch for release, and the Responsible Person (RP) who oversees a wholesale distributor’s GDP compliance. These are personal, named responsibilities — a service provider fills the role, but the legal duty attaches to the individual.

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What this page does not claim

The rings are SPEQ’s map of who operates in the regulated ecosystem, not a legal or regulatory classification. Where an organization type already has a canonical page, this points at it rather than describing it twice.

WHY THIS IS IN SPEQ’S SCOPE

QP certification is the legal gate to releasing a batch and the RP is legally accountable for GDP compliance — named roles without which product cannot lawfully reach the EU/UK market.

2. Product quality4. Regulatory status9. Inspection / audit readiness10. Ability to develop, manufacture, distribute, or support a regulated product

The regulated-relevance test — an adjacent subject belongs only when it materially affects one of ten regulated concerns.

WHAT THEY DO
  • Provide QP batch certification and release under EU/UK GMP
  • Act as the named Responsible Person for a wholesale-distribution authorisation
  • Oversee GDP compliance, supplier/customer qualification, and returns/falsified-medicine controls
  • Advise on importation and QP certification of third-country product
HOW IT TOUCHES THE QUALITY SYSTEM

QP certification is the legal gate to market: no batch is released for sale in the EU/UK without a QP’s certification under EU GMP Annex 16, and the QP must be satisfied the batch complies — a personal, non-delegable judgement.

The Responsible Person is personally accountable for a distributor’s GDP compliance under the EU GDP guidelines; the role cannot be reduced to a name on a licence who never exercises it.

Because these are named individual duties, a service arrangement must give the RP/QP genuine authority and access — an RP or QP who cannot actually oversee or refuse is a compliance fiction.

WHERE IT GOES WRONG
  • A named RP/QP who lacks real authority, time, or access to discharge the role
  • QP certification treated as a rubber stamp rather than a personal compliance judgement
  • Gaps at the importation/QP-certification interface for third-country product
STANDARDS AT THIS INTERFACE · 4
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The 4 standards SPEQ maps to this org type’s quality interface, across 3 regulatory bodies: ICH, EC, EMA.

FREQUENTLY ASKED

What is the difference between a QP and an RP?

A Qualified Person (QP) certifies each batch of a medicinal product for release under EU/UK GMP — the legal gate to market, governed by EU GMP Annex 16. A Responsible Person (RP) oversees a wholesale distributor’s Good Distribution Practice compliance under the EU GDP guidelines. Both are named, personal legal roles; one sits at manufacture/release, the other at distribution.

Can the QP or RP role really be outsourced?

The person can be a contractor, but the legal responsibility attaches to the named individual, not the company that supplies them — and it cannot be reduced to a name on a licence. A contract QP or RP must have genuine authority, time, and access to discharge the role, including the ability to refuse. An RP or QP who cannot actually oversee is a compliance fiction an inspector will see through.