← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #147 OF 1,000 MOST-CITED

Procedures for non-sterile drug products

FDA cited this observation 160 times across 151 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Drugs160
BY FISCAL YEAR
FY20268
FY202519
FY202421
FY202316
FY202219
FY202110
FY20206
FY201921
FY201824
FY201716

How FDA worded it — real examples

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not established, written and followed.

Gasco Industrial Corp. · Gurabo, Puerto Rico · Drugs · 2026-02-27

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not followed.

Tan-Alize Kozmetik ve Temizlik Urunleri Sanayi ve Ticaret A.S. · Cekmekoy · Drugs · 2026-02-27

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not established, written and followed.

CoreRX Inc. · Clearwater, Florida · Drugs · 2026-02-26

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not established and followed.

Tropical Seas, Inc. · Holly Hill, Florida · Drugs · 2026-02-12

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not followed.

Nice-Pak Products, LLC · Saint Louis, Missouri · Drugs · 2026-02-05

Procedures designed to prevent objectionable microorganisms in drug products not required to be sterile are not established.

Hibrow Healthcare Private Limited · Kancheepuram District · Drugs · 2026-01-30

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Contamination controlPharmaceutical quality systemPharma industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

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