← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #205 OF 1,000 MOST-CITED

Establish reliability of supplier's C of A

FDA cited this observation 114 times across 110 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Drugs114
BY FISCAL YEAR
FY20267
FY202515
FY202412
FY202310
FY202214
FY20219
FY20206
FY201913
FY201816
FY201712

How FDA worded it — real examples

Establishment of the reliability of the supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

New SPS Crossfolds, LLC · Commack, New York · Drugs · 2026-04-20

Establishment of the reliability of the component supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

Optimal Solution Labs LLC · Valencia, California · Drugs · 2026-04-17

Establishment of the reliability of the component supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

Blaine Labs Inc · Santa Fe Springs, California · Drugs · 2025-12-22

Establishment of the reliability of the component supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

Medtronic, Inc. · Minneapolis, Minnesota · Drugs · 2025-12-10

Establishment of the reliability of the component supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

Merle Norman Cosmetics, Inc. · Los Angeles, California · Drugs · 2025-11-21

Establishment of the reliability of the component supplier's report of analyses is deficient in that the test results are not appropriately validated at appropriate intervals.

BioMed Laboratories, LLC. · Dallas, Texas · Drugs · 2025-10-31

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Pharmaceutical quality systemPharma industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

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