← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #716 OF 1,000 MOST-CITED

System of process controls to prevent adulteration

FDA cited this observation 23 times across 15 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Foods23
BY FISCAL YEAR
FY20261
FY20256
FY20247
FY20235
FY20223
FY20181

How FDA worded it — real examples

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

Milchwerke "Mittelelbe" GmbH · Stendal · Foods · 2026-05-08

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

Synlait Milk Limited · Rakaia · Foods · 2025-09-26

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

PBM Nutritionals, LLC · Covington, Ohio · Foods · 2025-06-12

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

Milupa GmbH · Fulda · Foods · 2025-05-09

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

Nutribio, SA · Montauban · Foods · 2025-04-11

You did not establish a system of process controls covering all stages of processing that was designed to ensure that infant formula does not become adulterated due to the presence of microorganisms in the formula or in the processing environment.

Mead Johnson & Company, LLC · Zeeland, Michigan · Foods · 2025-01-10

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Food industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

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