← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #730 OF 1,000 MOST-CITED

Failure to meet specifications

FDA cited this observation 27 times across 27 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Drugs27
BY FISCAL YEAR
FY20222
FY20214
FY20202
FY20193
FY20187
FY20177
FY20162

How FDA worded it — real examples

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

Hetero Labs Limited (Unit V) · Mahabubnagar · Drugs · 2022-08-12

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

Glenmark Pharmaceuticals Limited · Solan · Drugs · 2022-06-22

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

EyePoint US, Inc. · Watertown, Massachusetts · Drugs · 2021-09-01

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

Teligent Pharma, Inc. · Buena, New Jersey · Drugs · 2021-08-31

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

Tris Pharma Inc. · Monmouth Junction, New Jersey · Drugs · 2021-06-08

An NDA-Field Alert Report was not submitted within three working days of receipt of information concerning a failure of one or more distributed batches of a drug to meet the specifications established for it in the application.

PF Consumer Healthcare BV (Puerto Rico Operations) LLC · Guayama, Puerto Rico · Drugs · 2021-03-17

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Quality risk managementPharma industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

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