← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #600 OF 1,000 MOST-CITED

Orderly handling, prevention of mix-ups, prevention of contamination

FDA cited this observation 31 times across 28 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Drugs31
BY FISCAL YEAR
FY20269
FY20255
FY20241
FY20234
FY20221
FY20211
FY20198
FY20182

How FDA worded it — real examples

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

Cardinal Health 414, LLC · Jackson, Mississippi · Drugs · 2026-03-18

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

University Of Texas MD Anderson Cancer Center: PET · Houston, Texas · Drugs · 2026-02-24

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

Biomedical Research Foundation of Northwest Louisiana · Shreveport, Louisiana · Drugs · 2026-02-20

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

PETNET Solutions Inc · Cleveland, Ohio · Drugs · 2026-02-17

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

Cardinal Health 414 LLC · Phoenix, Arizona · Drugs · 2026-01-23

Your facilities are not adequate to ensure the prevention of contamination of equipment or product by substances, personnel, or environmental conditions that could reasonably be expected to have an adverse effect on product quality.

P.E.T.NET HOUSTON, LLC · Houston, Texas · Drugs · 2026-01-20

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Contamination controlPharma industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

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