← 483 OBSERVATION EXPLORER

FDA 483 OBSERVATION · #478 OF 1,000 MOST-CITED

Late submission of 15-day report

FDA cited this observation 39 times across 34 firms in recent inspections. Below: how it breaks down by program area and fiscal year, and real examples of how FDA worded it on Form FDA 483.

BY PROGRAM AREA
Drugs39
BY FISCAL YEAR
FY20261
FY20256
FY20248
FY20231
FY20221
FY20211
FY20201
FY20196
FY20188
FY20176

How FDA worded it — real examples

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Ascendis Pharma LLC · Palo Alto, California · Drugs · 2026-03-06

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Upsher-Smith Laboratories, LLC · Maple Grove, Minnesota · Drugs · 2025-08-08

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Novo Nordisk Inc. · Plainsboro, New Jersey · Drugs · 2025-02-07

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Bracco Diagnostics, Inc. · Princeton, New Jersey · Drugs · 2024-11-27

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Acrotech Biopharma Inc. · East Windsor, New Jersey · Drugs · 2024-11-18

Not all adverse drug experiences that are both serious and unexpected have been reported to FDA within 15 calendar days of initial receipt of the information.

Alexion Pharmaceuticals, Inc. · Boston, Massachusetts · Drugs · 2024-11-07

Related SPEQ references

Where to read the requirements behind this observation area on SPEQ. These are SPEQ's topic and audience pages — not an FDA classification of the citation.

Pharma industry

Examples are a representative sample of FDA's published inspection observations. SPEQ is not affiliated with the FDA; this is a reference view of public FDA data.

Weekly Briefing

Get the Weekly GxP Briefing

Curated regulatory intelligence — enforcement, recalls, guidance, and quality signals — in one practitioner-grade email each week. Free.

Read a past issue →